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| Catalog Number | orb1307105 |
|---|---|
| Category | Small Molecules |
| Description | Alpelisib |
| CAS Number | 1217486-61-7 |
| Purity | 99.73% |
| MW | 441.47 |
| SMILES | Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1ccnc(c1)C(C)(C)C(F)(F)F |
| Formula | C19H22F3N5O2S |
| Biological Activity | Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity. Alpelisib inhibits PI3Kβ/γ/δ with low activity (IC50=250/290/1200 nM). Alpelisib has antitumor activity and is targeted to PIK3CA mutant tumors. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Alpelisib(BYL-719) [orb180951]
[1217486-61-7]
441.47
C19H22F3N5O2S
1 ml x 10 mm (in DMSO), 100 mg, 1 g, 250 mg 
