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Catalog Number | orb1961355 |
---|---|
Category | Small Molecules |
Description | AKR1C3 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 38 KDa, reducing conditions |
Biological Activity | AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human AKR1C3(Met1-Tyr323) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
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