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Catalog Number | orb147678 |
---|---|
Category | Antibodies |
Description | Rat monoclonal to Aha1 (ATTO-488). Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors.. |
Species/Host | Rat |
Clonality | Monoclonal |
Clone Number | 25F2.D10 |
Tested applications | ELISA, ICC, IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | IgG2a Kappa |
Immunogen | Mouse Aha1 |
Concentration | 1.59 mg/ml |
Dilution range | WB (1:1000), IHC (1:100), ICC/IF (1:1000), IP ( 1:1000) |
Conjugation | ATTO-488 |
MW | 38kDa |
Target | AHA1 |
Entrez | 217737 |
UniProt ID | Q8BK64 |
NCBI | NP_666148.1 |
Storage | Conjugated antibodies should be stored at 4°C |
Buffer/Preservatives | 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2 *Storage buffer may change when conjugated |
Alternative names | Aha 1 antibody, Ahsa1 antibody, p38 antibody, HSPC Read more... |
Note | For research use only |
Application notes | 1 µg/ml of SMC-173 was sufficient for detection of Aha1 in 10 µg of rat tissue lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody. |
Expiration Date | 12 months from date of receipt. |
ELISA, FC, ICC, IF, IHC, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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