Afuresertib (GSK2110183)

• Catalog Number: orb315494
• Category: Small Molecules
• Description: Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
• CAS Number: [1047644-62-1]
• MW: 427.3232
• SMILES: ClC1=C(C2=C(C([H])=NN2C([H])([H])[H])Cl)C([H])=C(C(N([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C2C([H])=C([H])C([H])=C(C=2[H])F)=O)S1
• Formula: C₁₈H₁₇CL₂FN₄OS
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Afuresertib (GSK2110183)