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Afegostat HCl

Afegostat HCl

Catalog Number: orb1703809

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Catalog Numberorb1703809
CategorySmall Molecules
DescriptionAfegostat HCl
Purity98.00%
MW183.63
Biological ActivityAfegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug for the treatment of certain forms of Gaucher's disease.
CAS Number161302-93-8
FormulaC6H14ClNO3
SMILESC(O)[C@@H]1[C@@H](O)[C@H](O)CNC1.Cl
Storage-20°C
NoteFor research use only