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Catalog Number | orb1703809 |
---|---|
Category | Small Molecules |
Description | Afegostat HCl |
Purity | 98.00% |
MW | 183.63 |
Biological Activity | Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug for the treatment of certain forms of Gaucher's disease. |
CAS Number | 161302-93-8 |
Formula | C6H14ClNO3 |
SMILES | C(O)[C@@H]1[C@@H](O)[C@H](O)CNC1.Cl |
Storage | -20°C |
Note | For research use only |