ADAM 17 antibody

• Catalog Number: orb137133
• Category: Antibodies
• Description: Rabbit polyclonal to ADAM 17. This gene encodes a disintegrin and metalloprotease (ADAM) domain 17, which is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. This gene contains 19 exons and alternative splicing generates 2 transcripts.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Dilution range: WB:1:500-1:1000
• Conjugation: Unconjugated
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of HT1080 whole cell lysate using ADAM 17 antibody