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ACYP2 Protein, Human, Recombinant (GST)
Catalog Number: orb1957375
| Catalog Number | orb1957375 |
|---|---|
| Category | Proteins |
| Description | Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 and TSPYL6 associated with shorter telomere length. The research showed that that the G allele of rs11896604 and the A allele of rs12615793 within ACYP2 gene, rs12615793- smoking interaction, and rs11896604-alcohol drinking interaction were all associated with increased IS risk. |
| Tag | N-GST |
| Purity | 98.00% |
| MW | 38.2 kDa (predicted); 35 kDa (reducing conditions) |
| UniProt ID | P14621 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 and TSPYL6 associated with shorter telomere length. The research showed that that the G allele of rs11896604 and the A allele of rs12615793 within ACYP2 gene, rs12615793- smoking interaction, and rs11896604-alcohol drinking interaction were all associated with increased IS risk. |
| Expression Region | A DNA sequence encoding the human ACYP2 (P14621) (Ser 2-Tyr 99) was fused with the GST tag at the N-terminus. Predicted N terminal: Met |
| Storage | -20°C |
| Note | For research use only |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expiration Date | 6 months from date of receipt. |
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Human ACYP2 protein [orb391199]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μgRecombinant Human ACYP2 Protein, Gst Tag [orb1552964]
≥90% as determined by SDS-PAGE
This protein contains the human ACYP2(Ser2-Tyr99) was fused with the N-terminal Gst Tag and expressed in E. coli.
100 μg, 50 μg
