A-849519

• Catalog Number: orb1741074
• Category: Small Molecules
• Description: A-849519
• CAS Number: 904680-01-9
• Purity: 0.98
• MW: 432.51
• SMILES: C(O)(=O)C1=C2C(=CC=C1NS(=O)(=O)C3=C(/C=C\CN(C)C)C=C(F)C=C3)CCCC2
• Formula: C₂₂H₂₅FN₂O₄S
• Biological Activity: A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.