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Catalog Number | orb1740134 |
---|---|
Category | Small Molecules |
Description | A-357300 |
CAS Number | 369358-07-6 |
Purity | 0.98 |
MW | 359.87 |
SMILES | C(NNC([C@H]([C@@H](CCSC(C)C)N)O)=O)(=O)C1=CC(Cl)=CC=C1 |
Formula | C15H22ClN3O3S |
Biological Activity | A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM. Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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