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Catalog Number | orb1302101 |
---|---|
Category | Small Molecules |
Description | 5-Aminovaleric acid |
CAS Number | 660-88-8 |
Purity | 98% |
MW | 117.15 |
SMILES | NCCCCC(O)=O |
Formula | C5H11NO2 |
Biological Activity | 5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction: L-lysine leads to cadverine leads to L-piperideine leads 5-aminovalerate . In other words it is a metabolite of cadaverine which is formed via the intermediate, 1-piperideine. Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue. High levels of 5-aminovalerate in biofluids may indicate bacterial overgrowth or endogenous tissue necrosis. In most cases endogenous 5-aminovalerate is thought to be primarily a microbial metabolite produced by the gut or oral microflora, although it can be produced endogenously. 5-aminopentanoic acid is an in vivo substrate of 4-aminobutyrate:2-oxoglutarate aminotransferase . |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |