4-Hydroxychalcone

SKU: orb1304630

Description

This small molecule, 4-Hydroxychalcone, has been shown to mitigate hyperaldosteronism, inflammation, and renal injury in cryptochrome-deficient murine models. It serves as a useful research tool for studying chronobiology, steroid hormone pathways, and cardiorenal pathophysiology in both in vivo and in vitro experimental systems.

Research Area

Signal Transduction

Key Properties

• CAS Number: 20426-12-4
• MW: 224.25
• Purity: >99.99% (May vary between batches)
• Formula: C₁₅H₁₂O₂
• SMILES: OC1=CC=C(\C=C\C(=O)C2=CC=CC=C2)C=C1
• Target: NF-κB
• Solubility: DMSO:45 mg/mL (200.67 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.92 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4 Hydroxychalcone, 4Hydroxychalcone, 4-Hydroxychalcone, inhibit, Nuclear factor-κB, Nuclear factor-kappaB, NFkB, NF-kB, NFκB, NF-κB, P-Cinnamoylphenol, Inhibitor

Compound Identifiers

PubChem CID

5282361