3-MATIDA

SKU: orb1304156

Description

3-MATIDA is a selective mGluR1 antagonist (IC50: 6.3 μM) with over 40-fold selectivity versus other mGluR subtypes, NMDA, and AMPA receptors. It has demonstrated neuroprotective effects in in vitro models, including murine cortical cell cultures and rat hippocampal slice cultures, supporting its research use in studying excitotoxicity and neurological disorders.

Research Area

Neuroscience

Key Properties

• CAS Number: 518357-51-2
• MW: 215.23
• Purity: 99.96% (May vary between batches)
• Formula: C₈H₉NO₄S
• SMILES: C(C(O)=O)(N)C=1SC(C(O)=O)=CC1C
• Target: GluR,NMDAR,Others
• Solubility: DMSO:2.16 mg/mL (10.04 mM);1eq. NaOH:50 mM

Bioactivity

• Target IC50:
  GluR(AMPA):250 μM|mGluR1:6.3 μM|mGluR5:> 300 μM|NMDA:250 μM|mGluR2:> 300 μM|mGluR4:> 300 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3MATIDA, 3-MATIDA, 3 MATIDA, mGluR1, NMDA

Compound Identifiers

PubChem CID

10398360