3-Hydroxy Midostaurin

SKU: orb1990795

Description

3-Hydroxy Midostaurin (CGP 52421) is an active metabolite of PKC412 that potently inhibits FLT3 autophosphorylation, demonstrating significant cytotoxicity in cellular assays. This compound is a valuable research tool for studying FLT3-driven hematological malignancies in both in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 179237-49-1
• MW: 586.648
• Formula: C₃₅H₃₀N₄O₅
• SMILES: CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4C(O)NC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
• Target: FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137552093