11Beta-hydroxyprogesterone

SKU: orb1685174

Description

11β-Hydroxyprogesterone is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). It is used in research to study corticosteroid metabolism and receptor activation in cellular models like COS-7 cells, with applications in exploring hypertension and metabolic syndrome mechanisms.

Research Area

Metabolism Research

Key Properties

• CAS Number: 600-57-7
• MW: 330.46
• Purity: 99.52%
• Formula: C₂₁H₃₀O₃
• SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C
• Target: Endogenous Metabolite,Dehydrogenase
• Solubility: DMSO:15 mg/mL (45.39 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.05 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

11Betahydroxyprogesterone, 11Beta-hydroxyprogesterone, 11b-hydroxyprogesterone, 11Beta hydroxyprogesterone, 11β-HSD1, 11β-Hydroxyprogesterone, Sodium Channel

Compound Identifiers

PubChem CID

101788