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DPP-1-IN-1

SKU: orb3135531

Description

DPP-1-IN-1 (Compound 14) is an orally active inhibitor of cathepsin C (also known as dipeptidyl peptidase I), with an IC50 of 5.31 nM. It effectively suppresses downstream neutrophil elastase activity in neutrophils mediated by cathepsin C. DPP-1-IN-1 is applicable for studying inflammatory diseases.

Research Area

Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number2781135-27-9
MW420.44
FormulaC23H21FN4O3
SMILESFC=1C=C2C=3C(COC2=CC1C[C@H](NC(=O)[C@@H]4CNCCCO4)C#N)=CC(C#N)=CC3
TargetDipeptidyl Peptidase

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information