AVS Bio - mouse modified citrulline antibody

SKU: MQR1.602

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Description

This antibody is developed for the detection of citrulline containing proteins. The amino acid citrulline is generated by posttranslational modification of arginine by peptidylarginine-deiminases (PADs; MQ16.201 and MQ16.203). Antibodies directed to citrulline containing proteins (e.g. histones) are detected in rheumatoid arthritis patients.

Images & Validation

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Tested Applications	ELISA, WB
Dilution Range	ELISA: 0.08 – 0.5 µg/ml WB: 1 µg/ml Unless the stability in the actual test system has been established, it is recommended to dilute the product immediately before use.
Reactivity	Human

Key Properties

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Clonality	Monoclonal
Isotype	Mouse IgG2a, κ
Clone No.	C4S
Immunogen	Citrulline-containing peptide modified with 2,3-butanedione monoxime and antipyrine.
Target	citrulline, modified
Purification	Protein A purified.
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	solution
Buffer/Preservatives	The antibody is supplied in PBS.
Expiration Date	For shelf life and expiration details, please refer to the Certificate of Analysis (CoA).
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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