2-Furoic acid

SKU: orb1220862

Description

2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.

Key Properties

• CAS Number: 88-14-2
• MW: 112.08
• Purity: >98% (HPLC)
• Formula: C₅H₄O₃?
• SMILES: OC(=O)c1ccco1
• Target: Antifection
• Solubility: DMSO:100 mg/mL (892.22 mM)

Bioactivity

• In Vivo:
  2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels. 2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities. 2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice.
  Read more...

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Furan-2-carboxylic acid

Quick Database Links

Gene Symbol

Antifection