Picroside I

SKU: orb1222429

Description

Picroside I, a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug candidates for cancer therapy by suppressing Collagenases and Gelatinases. Picroside I can enhance basic fibroblast growth factor(bFGF)-, staurosporine- or dbc-mitogen-activated protein (MAP)-induced neurite outgrowth from PC12D cells.

Key Properties

• CAS Number: 27409-30-9
• MW: 492.47
• Purity: >98% (HPLC)
• Formula: C₂₄H₂₈O₁₁
• SMILES: c1ccc(cc1)/C=C/C(=O)O[C@H]1[C@@H]2C=CO[C@H]([C@@H]2[C@@]2([C@H]1O2)CO)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO
• Target: Antifungal
• Solubility: In Vitro: DMSO : 250 mg/mL (507.65 mM)

Bioactivity

• In Vivo:
  Animal model: Ovalbumin (OVA) systematic sensitization BALB/c mice model. Dosage: 0.2, 2.0 and 20 mg/kg. Administration: Orally, once daily, from day 20 to day 32. Result: Inhibited allergen-triggered inflammatory cell infiltration.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antifungal