Paromomycin Sulfate

• Catalog Number: orb1309761
• Category: Small Molecules
• Description: Paromomycin Sulfate
• CAS Number: 1263-89-4
• Purity: 99.82%
• MW: 713.71
• SMILES: OS(O)(=O)=O.NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
• Formula: C₂₃H₄₇N₅O₁₈S
• Biological Activity: Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed by cell death. Paromomycin Sulfate (Aminosidine sulfate) is the sulfate salt form of paromomycin, a structural derivative of neomycin, an aminoglycoside antibiotic with amebicidal and bactericidal effects against predominantly aerobic gram-negative bacteria.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.