Naproxen

SKU: orb1308096

Description

Naproxen, the (S)-enantiomer of this propionic acid-derived NSAID, exhibits analgesic, antipyretic, and anti-inflammatory properties. It is widely used in research to study inflammation and pain mechanisms, both in vitro (e.g., COX enzyme inhibition assays) and in vivo (animal models of inflammation).

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 22204-53-1
• MW: 230.26
• Purity: 99.91% (May vary between batches)
• Formula: C₁₄H₁₄O₃
• SMILES: [C@H](C(O)=O)(C)C1=CC2=C(C=C(OC)C=C2)C=C1
• Target: COX|||Autophagy
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.69 mM);DMSO:45 mg/mL (195.43 mM)

Bioactivity

• Target IC50:
  COX-2:5.15 μM|COX-1:8.72 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, (S)-Naproxen, Cyclooxygenase, COX, Naproxen, Inhibitor, inhibit

Compound Identifiers

PubChem CID

156391