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Sorafenib
Catalog Number: orb1310944
| Catalog Number | orb1310944 |
|---|---|
| Category | Small Molecules |
| Description | Sorafenib |
| CAS Number | 284461-73-0 |
| Purity | 99.69% |
| MW | 464.82 |
| SMILES | O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2 |
| Formula | C21H16ClF3N4O3 |
| Biological Activity | Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity and can induce autophagy and apoptosis as well as agonistic ferroptosis. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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Regorafenib (BAY73-4506,Fluoro-Sorafenib) [orb154627]
[755037-03-7]
482.82
C21H15ClF4N4O3
1 g, 100 mg, 250 mg, 1 ml x 10 mm (in DMSO) - Item 1 of 1
