RAS activator compound 1

SKU: orb746410

Description

RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2.

Key Properties

• CAS Number: 1579978-17-8
• MW: 449.983
• Purity: >98%
• Formula: C₂₅H₂₈ClN₅O
• SMILES: C(NC1CCN(CC2C3=C(NC=2)C=CC(Cl)=C3)CC1)(=O)[C@H](N)CC1C2=C(NC=1)C=CC=C2

Storage & Handling

• Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
• Disclaimer: For research use only

Chemical Structure: 1579978-17-8