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Catalog Number | orb1305557 |
---|---|
Category | Small Molecules |
Description | Pirfenidone |
CAS Number | 53179-13-8 |
Purity | 99.79% |
MW | 185.22 |
SMILES | O=C1N(C=C(C)C=C1)C2=CC=CC=C2 |
Formula | C12H11NO |
Biological Activity | Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[53179-13-8] | |
185.22 | |
C12H11NO |