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PD-1/PD-L1-IN-23

SKU: orb1744749

Description

PD-1/PD-L1-IN-23 is a potent, orally active ester prodrug of L7, a benzooxadiazole derivative, that functions as an inhibitor of PD-1/PD-L1. It has undergone biological evaluation for its inhibitory effects on PD-L1, showing significant antitumor effects in both syngeneic tumor models and PD-L1 humanized mice.

Images & Validation

Key Properties

CAS Number2597056-04-5
MW703.41
FormulaC32H30BrCl2N3O6
SMILESO(CC1=CC=2C(C=C1)=NON2)C3=C(CN[C@@H](C(OCC)=O)CO)C=C(Cl)C(OCC4=C(Br)C(=CC=C4)C5=CC=CC=C5)=C3.Cl
TargetPD-1/PD-L1,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

PD-1/PD-L1-IN-23 (orb1744749)

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