Mca-(ala7,lys(dnp)9)-bradykinin

• Catalog Number: orb2278620
• Category: Small Molecules
• Description: Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1].
• CAS Number: 323577-36-2
• Purity: 98.00%
• MW: 1388.44
• SMILES: C(C(N[C@H](C(=O)N1[C@H](C(=O)N2[C@H](C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCNC5=C(N(=O)=O)C=C(N(=O)=O)C=C5)C(O)=O)=O)=O)C)=O)CO)=O)=O)=O)CCC2)CCC1)CCCNC(=N)N)=O)C=6C=7C(=CC(OC)=CC7)OC(=O)C6
• Formula: C₆₆H₈₁N₁₅O₁₉
• Biological Activity: Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,4-dinitrophenyl (Dnp) group for quenching, yielding a significant increase in fluorescence when the substrate is cleaved [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.