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Cath-L-dBET1

SKU: orb3028881

Description

Cath-L-dBET1 is a PROTAC degrader targeting BRD4. It has an IC50 value of 2.8 μM in MDA-MB-231 cells. Activated by cathepsin L (Cath-L), Cath-L-dBET1 recruits E3 ubiquitin ligase to degrade BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable for antitumor research.

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Key Properties

TargetPROTACs,Epigenetic Reader Domain

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

Cath-L-dBET1 (orb3028881)

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