Angiopeptin TFA

SKU: orb1981419

Description

Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, acts as a partial agonist at sst 2/sst 5 receptors, with IC50 values of 0.26 nM and 6.92 nM, respectively. It effectively inhibits the release of growth hormone and the production of insulin-like growth factor-1 (IGF-1), and either inhibits adenylate cyclase activity or promotes extracellular acidification. Angiopeptin TFA shows promise for use in coronary atherosclerosis research.

Key Properties

• CAS Number: 2478421-60-0
• MW: 1326.39
• Formula: C₅₈H₇₃F₆N₁₁O₁₄S₂
• SMILES: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(N)=O
• Target: Somatostatin,AChR

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Somatostatin,AChR