Firocoxib

SKU: orb1299676

Description

Firocoxib (ML 1785713) is a potent and selective COX-2 inhibitor (IC50 = 0.13 µM) used in veterinary medicine for its anti-inflammatory properties. It is a valuable research tool for studying COX-2 biology and inflammation mechanisms in both in vitro enzymatic assays and in vivo models of pain and inflammation in species like dogs and horses.

Research Area

Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 189954-96-9
• MW: 336.4
• Purity: 99.84%
• Formula: C₁₇H₂₀O₅S
• SMILES: O(CC1CC1)C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3
• Target: COX
• Solubility: DMSO:47 mg/mL (139.71 mM)

Bioactivity

• Target IC50:
  COX-2:0.13 μM|COX-1:7.5 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, COX-2, Cyclooxygenase, anti-inflammatory, Firocoxib, fever, IC80, Inhibitor, inhibit, LPS, ML 1785713, ML1785713, ML-1785713, orally, safety

Compound Identifiers

PubChem CID

208910