CD123 Antibody

SKU: orb154404

Description

Mouse monoclonal antibody to CD123 which is also known as IL-3 receptor subunit alpha, IL-3R-alpha and IL3RA, is a single-pass type I membrane protein which is a member of the type I cytokine receptor family and Type 5 subfamily. CD123 is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. CD123 is also a useful new marker for distinguishing B-cell disorders with circulating villous lymphocytes.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: FC, IHC-Fr, IP, WB
• Reactivity: Human
• Application Notes:
  Flow cytometry: Recommended dilution: 1-4 μg/ml.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: 6H6
• Immunogen: IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
• Target: CD123
• Purification: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IL3RA, MGC34174, hIL-3Ra

Quick Database Links

Gene Symbol

CD123

UniProt

P26951

NCBI Gene ID

3563