Penetratin

• Catalog Number: orb1140599
• Category: Proteins
• Description: Cell penetrating peptide; Cell penetrating peptides.
• CAS Number: 188842-14-0
• Form/Appearance: Freeze dried solid
• Purity: > 95% by hplc
• MW: 2246.8 Da
• Formula: C₁₀₄H₁₆₈N₃₄O₂₀S
• Structure: H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH
• Solubility (25°C): Soluble in water
• Protein Sequence: RQIKIWFQNRRMKWKK
• Storage: Store dry, frozen and in the dark
• Alternative names: Antennapedia peptide, Antennapedia (43-58)
• Background: Penetratin is a 16-mer peptide derived from the third helix of the Drosophila Antennapedia DNA binding domain that is mapped to be responsible for cellular internalization. Penetratin is able to translocate through the plasma membrane to the cytosol and nucleus, and can facilitate internalization of macromolecular cargoes into living cells, usually by the formation of a conjugate or fusion protein. Penetratin is commonly used as an alternative or complement to Tat peptide for enhancing the cellular uptake of nanoparticles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.