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| Catalog Number | orb1980262 |
|---|---|
| Category | Antibodies |
| Description | Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate composed of the humanized monoclonal antibody zilovertamab linked to the anti-microtubule cytotoxin monomethyl auristatin E (MMAE). Upon binding to ROR1 on tumor cells, it is rapidly internalized and directed to lysosomes for cleavage, releasing MMAE and inducing apoptosis in targeted cells. Zilovertamab vedotin has potential applications in cancer research. |
| Target | Antibody-Drug Conjugates (ADCs) |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Antibody Type | Inhibitor Antibody |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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