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| Catalog Number | orb2565042 |
|---|---|
| Category | Small Molecules |
| Description | XRD-0394 is a highly effective and selective dual inhibitor of ATM and DNA-PKcs, exhibiting oral bioactivity. It notably increases tumor cell destruction both in vitro and in vivo when combined with therapeutic ionizing radiation. Furthermore, XRD-0394 enhances the efficacy of PARP and topoisomerase I inhibitors in vitro. |
| MW | 527.61 |
| CAS Number | 2595308-10-2 |
| Formula | C26H30FN5O4S |
| SMILES | O=C1C2(C=3C=4C(N=CC3N1C)=CC(F)=C(C4)C=5C=C(NS(C)(=O)=O)C(OCCNC(C)C)=NC5)CCC2 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)