Vem-L-Cy5

• Catalog Number: orb2278413
• Category: Small Molecules
• Description: Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), selectively targets the BRAF V600E mutation and inhibits MEK phosphorylation. This compound demonstrates cell permeability and has been shown to inhibit the growth of various cancer cell types.
• Target: Raf
• MW: 1194.31
• Formula: C₆₃H₆₈F₅N₇O₉S
• SMILES: CC(C1=C(N/2CCCCCC(NCCOCCOCC(NC3=CC=C(C4=CN=C(NC=C5C(C6=C(F)C=CC(NS(=O)(CCC)=O)=C6F)=O)C5=C4)C=C3)=O)=O)C=CC=C1)(C)C2=C/C=C/C=C/C7=[N+](C)C(C=CC=C8)=C8C7(C)C.FC(F)(F)C([O-])=O
• Storage: -20°C
• Research Area: Signal Transduction
• Note: For research use only
• Expiration Date: 12 months from date of receipt.