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Catalog Number | orb1708260 |
---|---|
Category | Small Molecules |
Description | VDR agonist 1 |
Purity | 98.00% |
MW | 509.77 |
Biological Activity | VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1]. |
CAS Number | 2269494-43-9 |
Formula | C32H51N3O2 |
SMILES | C(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2 |
Storage | -20°C |
Note | For research use only |