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VDR agonist 1

VDR agonist 1

Catalog Number: orb1708260

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Catalog Numberorb1708260
CategorySmall Molecules
DescriptionVDR agonist 1
Purity98.00%
MW509.77
Biological ActivityVDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].
CAS Number2269494-43-9
FormulaC32H51N3O2
SMILESC(CC)(CC)(C=1C=C(C(NCCN(CC)CC)=O)N(CC)C1)C2=CC(C)=C(/C=C/C(CC)(CC)O)C=C2
Storage-20°C
NoteFor research use only
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