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Catalog Number | orb216849 |
---|---|
Category | Proteins |
Description | Uroguanylin Human peptide |
CAS Number | 154525-25-4 |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
MW | 1667.89 |
Formula | C64H102N18O26S4 |
Protein Sequence | H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge Cys4-Cys12, Cys7-Cys15) |
Source | Synthetic |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Alternative names | UGN (human) Read more... |
Note | For research use only |
Application notes | Uroguanylin belongs to the guanylin family of cyclic guanosine monophosphate (cGMP) regulating peptides. This family of peptides shows homology to the heat stable enterotoxins produced by strains of Escherichia coli and other enteric bacteria that cause a secretory form of diarrhea. Along with the isolation of uroguanylin from urine and the subsequent demonstration of its natriuretic activity by direct effects on the kidney, uroguanylin has been suggested to play a role in the physiological maintenance of sodium balance in vivo. |
Expiration Date | 12 months from date of receipt. |
Human | |
31.25 pg/mL-2000 pg/mL | |
7.8 pg/mL |
Human | |
15.63-1000 pg/mL | |
5.7 pg/mL |
ELISA, WB | |
Greater than 90% by SDS-PAGE gel analyses | |
30.1 kDa | |
E.Coli |