TX-2552

• Catalog Number: orb2664302
• Category: Small Molecules
• Description: TX-2552 is an orally effective inhibitor of tyrosyl-DNA phosphodiesterase 1 (TDP1), with an IC50 value of 0.62 μM. It enhances the cleavage activity of topotecan in mouse bone marrow cells and amplifies the antitumor effects of topotecan in Krebs-2 ascites tumor-bearing mice.
• CAS Number: 2446767-14-0
• Purity: 98.00%
• MW: 392.46
• SMILES: O=C1C=C(C=2C(=CC(OC/C=C(/CCC=C(C)C)\C)=CC2)O1)C3=CC=C(F)C=C3
• Formula: C₂₅H₂₅FO₃
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.