TP-050

• Catalog Number: orb1744126
• Category: Small Molecules
• Description: TP-050 is a potent, selective NMDAR agonist that is orally active, showing EC50 values of 0.51 µM for GluN2A and 9.6 µM for GluN2D. This compound can cross the blood-brain barrier (BBB), enhancing hippocampal long-term (LTP) potentiation and neuronal signal transmission.
• Purity: 98.00%
• MW: 380.78
• Biological Activity: TP-050 is a potent, selective NMDAR agonist that is orally active, showing EC50 values of 0.51 µM for GluN2A and 9.6 µM for GluN2D. This compound can cross the blood-brain barrier (BBB), enhancing hippocampal long-term (LTP) potentiation and neuronal signal transmission.
• Formula: C₁₆H₁₅ClF₂N₆O
• SMILES: CC1=CN(C(=O)C2=CC(=NN12)CN3C(=CC(=N3)C(F)F)Cl)[C@H](C)CC#N
• Storage: -20°C
• Note: For research use only