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Catalog Number | orb1961107 |
---|---|
Category | Proteins |
Description | Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known. |
Tag | C-6xHis |
Purity | 98.00% |
Protein Sequence | Ser34-Asp374 |
UniProt ID | Q8NBK3 |
MW | 38-42 KDa (reducing condition) |
Application notes | 0 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known. |
Expression Region | Ser34-Asp374 |
Storage | -20°C |
Note | For research use only |
> 90% as determined by SDS-PAGE. | |
30 kDa |