SU-909

• Catalog Number: orb1089679
• Category: Small Molecules
• Description: SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM); inhibits FCS-stimulated phosphorylation of p100 in U2OS cells with IC50 of 8.8 uM, inhibits the noncanonical NF-kB pathway without affecting IKKβ-dependent IKappa-Bα loss in the canonical pathway.
• MW: 314.322499752045
• CAS Number: [2126749-48-0]
• Formula: C₁₃H₁₀N₆O₂S
• SMILES: S(C1C=CC(=CC=1)C1=C2C(C#N)=CNC2=NC(N)=N1)(N)(=O)=O
• Note: For research use only