STL1267

• Catalog Number: orb1744166
• Category: Small Molecules
• Description: STL1267 is a REV-ERB agonist that can cross the blood-brain barrier and inhibits BMAL1 gene expression. It can be used to study chronic diseases and inflammatory pain.
• Purity: 99.19%
• MW: 322.75
• Biological Activity: STL1267, a potent REV-ERB agonist capable of crossing the blood-brain barrier, exhibits a K i value of 0.16 µM for REV-ERBα without demonstrating cytotoxicity. It effectively inhibits the gene expression of BMAL1.
• CAS Number: 1429024-58-7
• Formula: C₁₇H₁₁ClN₄O
• SMILES: ClC1=NN=C2C=CC(=NN12)OC=3C=CC=CC3C=4C=CC=CC4
• Storage: -20°C
• Note: For research use only