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Catalog Number | orb2663905 |
---|---|
Category | Small Molecules |
Description | SR1555 hydrochloride is the hydrochloride salt form of SR1555. It acts as an inverse agonist for the retinoic acid receptor-related orphan receptor γ (RORγ), with an IC50 of 1 μM. This compound inhibits the development and function of pro-inflammatory TH17 cells while increasing the frequency of anti-inflammatory regulatory T (Treg) cells. SR1555 hydrochloride is utilized in research related to autoimmune diseases. |
Purity | 98.00% |
MW | 496.87 |
CAS Number | 2309312-90-9 |
Formula | C22H23ClF6N2O2 |
SMILES | Cl.O=C(N1CCN(CC2=CC=C(C=C2)C=3C=CC(=CC3)C(O)(C(F)(F)F)C(F)(F)F)CC1)C |
Storage | -20°C |
Note | For research use only |