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SPD304
Catalog Number: orb573330
| Catalog Number | orb573330 |
|---|---|
| Category | Small Molecules |
| Description | SPD304 is a selective inhibitor of tumor necrosis factor α (TNFα) and promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor, with an IC50 of 22 μM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α. |
| MW | 547.610598564148 |
| CAS Number | [869998-49-2] |
| Formula | C32H32F3N3O2 |
| SMILES | CN(CCN(C)CC1C2C(=CC=CC=2)N(C=1)C3C=C(C=CC=3)C(F)(F)F)CC4C(=O)C5C(OC=4)=CC(C)=C(C)C=5 |
| Note | For research use only |
SPD304 dihydrochloride [orb1309068]
99.25%
1049741-03-8
620.53
C32H34Cl2F3N3O2
100 mg, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 1 ml x 10 mM (in DMSO)
