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SIC-19
Catalog Number: orb2646361
Product Properties
| Catalog Number | orb2646361 |
|---|---|
| Category | Small Molecules |
| Description | SIC-19, a SIK2 inhibitor, functions by promoting the degradation of SIK2 protein via the ubiquitination pathway. It inhibits the growth of cancer cells and sensitizes cells, ovarian cancer organoids, and xenograft models to PARP inhibitors (such as Olaparib). |
| Target | SIK |
| MW | 574.67 |
| CAS Number | 713112-69-7 |
| Formula | C29H26N4O5S2 |
| SMILES | O=C(NC(=S)NNC(=O)C1=C(SC(=C1C2=CC=C(OC)C(OC)=C2)C)NC(=O)C=3C=CC=CC3)C=4C=CC=CC4 |
| Storage | -20°C |
| Research Area | Signal Transduction |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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