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Catalog Number | orb1303917 |
---|---|
Category | Small Molecules |
Description | Sesamol |
CAS Number | 533-31-3 |
Purity | 99.90% |
MW | 138.12 |
SMILES | OC1=CC2=C(OCO2)C=C1 |
Formula | C7H6O3 |
Biological Activity | Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |