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| Catalog Number | orb607188 |
|---|---|
| Category | Antibodies |
| Description | May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation. [UniProt] |
| Clonality | Monoclonal |
| Species/Host | Mouse |
| Isotype | Mouse IgG1, kappa |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | A recombinant human partial protein corresponding to amino acids 3-139 was used as the immunogen for the SERBP1 antibody. |
| UniProt ID | Q8NC51 |
| Tested applications | IHC-P |
| Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) |
| Application notes | Optimal dilution of the antibody should be determined by the researcher. |
| Antibody Type | Primary Antibody |
| Clone Number | PARB1-1 |
| Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Research Area | Epigenetics |
| Note | For research use only |

IHC testing of FFPE human urothelial carcinoma with SERBP1 antibody (clone PARB1-1). Required HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.
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