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SAFB (C) Antibody, Rabbit Polyclonal
Catalog Number: orb131814
| Catalog Number | orb131814 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to SAFB. Scaffold attachment factor B (SAFB) is a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). SAFB is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. SAFB is thought to serve as a molecular base to assemble a transcriptosome complex in the vicinity of actively transcribed genes. SAFB is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human |
| Immunogen | C-terminal region of human SAFB |
| Concentration | 100 μg/ml BSA |
| Dilution range | WB:1:1000-1:3000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 103 |
| UniProt ID | Q15424 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti Scaffold attachment factor B1 antibody, anti Read more... |
| Note | For research use only |
| Application notes | < strong>WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. < br>< strong>Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SAFB. |
| Expiration Date | 12 months from date of receipt. |
