Rhynchophylline

• Catalog Number: orb1300242
• Category: Small Molecules
• Description: Rhynchophylline
• CAS Number: 76-66-4
• Purity: 99.44%
• MW: 384.47
• SMILES: CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C(=O)Nc1ccccc31
• Formula: C₂₂H₂₈N₂O₄
• Biological Activity: 1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.