Randox - Pro-Matrix Metalloproteinase 9 (PRO MMP-9)

• Catalog Number: RCP9380
• Category: Proteins
• Description: Matrix metalloproteinases are a family of zinc- and calcium-dependant endopeptidases, which degrade extracellular matrix proteins. MMP-9 is secreted as a 92kDa zymogen. Cleavage of pro-MMP-9 results in the active enzyme with a molecular weight of ~82kDa. MMP-9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagenhomologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodelling, wound healing, tumour growth and metastasis.
• Tag: N terminal containing a HIS tag
• Form/Appearance: Liquid
• Buffer/Preservatives: 1XPBS, 50% Glycerol
• Purity: > 95 %, by SDS-PAGE under reducing conditions
• Protein Length: Ala20-Asp707
• UniProt ID: P14780
• MW: 78.59 kDa
• Application notes: ELISA, Western Blotting, etc.
• Expression System: E.coli
• Source: E.coli -derived human recombinant protein
• Storage: at -20 °C
• Alternative names: Matrix metalloproteinase 9, gelatinase B, 92kD gel
• Note: For research use only