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Catalog Number | RCP9090 |
---|---|
Category | Proteins |
Description | PAI-1 is a serine protease inhibitor, which can exist, either in an active inhibitory conformation or in an inactive or latent conformation. PAI-1 is produced mainly by the endothelium but is also secreted by other tissue types including adipose tissue. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, therefore inhibiting fibrinolysis. Increased levels of PAI-1 have been linked with various conditions including cardiovascular disease, thrombosis, insulin resistance and obesity. |
Tag | N terminal containing a HIS tag |
Form/Appearance | Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH 6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol). |
Purity | > 95 %, by SDS-PAGE under reducing conditions |
MW | 47.27 kDa |
UniProt ID | P05121 |
Protein Length | Val24-Pro402 |
Source | E.coli -derived human recombinant protein |
Expression System | E.coli |
Storage | at -20 °C |
Buffer/Preservatives | 1X Laemmli buffer |
Alternative names | Plasminogen activator inhibitor 1; Endothelial pla Read more... |
Note | For research use only |
Application notes | ELISA, Western Blotting, etc. |
Expiration Date | 6 months from date of receipt. |