Randox - Matrix Metalloproteinase-9 (MMP-9) (Western Blot Control)

• Catalog Number: RCP9308
• Category: Proteins
• Description: Matrix metalloproteinases are a family of zinc and calciumdependent endopeptidases, which degrade extracellular matrix proteins. MMP-9 is secreted as a 92kDa zymogen. Cleavage of pro-MMP-9 results in the active enzyme with a molecular weight of ~82kDa. MMP-9 has a gelatinbinding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodelling, wound healing, tumour growth and metastasis.
• Tag: N terminal containing a HIS tag
• Form/Appearance: Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH 6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).
• Buffer/Preservatives: 1X Laemmli buffer
• Purity: > 95 %, by SDS-PAGE under reducing conditions
• Protein Length: Asp113- Glu450
• UniProt ID: P14780
• MW: 42.03 kDa
• Application notes: ELISA, Western Blotting, etc.
• Expression System: E.coli
• Source: E.coli -derived human recombinant protein
• Storage: at -20 °C
• Alternative names: Matrix metalloproteinase 9, gelatinase B, CLG4B, G
• Note: For research use only